Funding Research to Save Lives

Our Mission

To accelerate the discovery of treatments and cures for Wolfram Syndrome and eventually other rare and ultra-rare diseases.

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About Wolfram Syndrome

Wolfram Syndrome is a rare genetic condition caused by mutations in the WFS1 gene, impacting roughly 2,000 individuals in the U.S. and approximately 20,000 worldwide. Currently there is no cure.

Children with the WFS1 gene mutation are usually diagnosed at age 6. Distinctive complications include diabetes, loss of vision due to optic nerve atrophy, loss of hearing, and progressive neurodegeneration. Consequently, prognoses are extremely poor with a median lifespan of 30-40 years.   With no current cure, effective disease modifying treatments are urgently needed.

In the US alone, 30 million people are affected by approximately 7,000 known rare and ultra-rare diseases. Many are life-threatening, and very few have FDA-approved treatments. About 45% of these diseases are neurological disorders, and 90% of rare childhood disorders have major neurological effects.

In general, the medical industry targets a cure for the masses, while efforts surrounding rare & ultra-rare diseases typically remain sidelined due to a lack of funding. While a singular rare or ultra-rare disease may only impact a small percentage of lives, in aggregate these diseases impact 1 in 10 individuals in our country.

Be a Tiger Foundation humbly strives to achieve an immediate impact in the ultra-rare disease space. We are a nonprofit 501(c)(3) organization, and through your generous donations, we directly fund and support clinical research aimed to treat and cure Wolfram Syndrome. The expectation is that 100% of your contributions made to the foundation will go toward funding a cure, so that your generosity will have maximum impact on patients and families affected by this disease.

Your donation dollars provide hope… inspiring kids and families to BE A TIGER while winning the fight against Wolfram Syndrome.

research the latest advances

Wolfram Syndrome Research Alliance

The Wolfram Syndrome Research Alliance (WSRA) serves as a centralized portal to connect researchers and clinicians, coordinating their efforts to quickly and effectively develop treatments and a cure for Wolfram Syndrome.

WSRA supports relationships between researchers while aligning scientists, clinicians, patients, governmental and non-profit agencies to further efforts towards effective Wolfram Syndrome treatment. Click the link below for the WS Treatment Pipeline.

Pleased to Meet You

Our Team

“Hope lies in dreams, in imagination, and in the courage of those who dare to make dreams into reality.”

– Jonas Salk

Derik Liberatore


25 Years Financial Services Industry

B.A. Colgate University, 1996

Born in McKeesport, PA

Lauren Liberatore

Co-Founder and COO

4 Years Accounting & Auditing

10 Years Pharmaceutical Industry

B.S. California Polytechnic State University, 2002

Born in Carmel, CA

company we keep

Our Partners

“Not one of us, including me, ever does great things. But we can all do small things, with great love. And together we can do something magnificent.”

– Mother Teresa

Hackensack Meridian Health
Institute for Neuroscience Montpellier
Snow Foundation

Contact derik and lauren

Give us a ring, we’d love to chat with you.

Whether you want to learn more about the disease, patient advocacy, or our fundraising efforts, please don’t hesitate to reach out.

“Life’s like a movie, write your own ending.”

– Jim Henson